发明名称 |
AMINO ACID SEQUENCES WHICH ENHANCE PEPTIDE CONJUGATE SOLUBILITY |
摘要 |
The present invention provides peptide conjugates having improved solubility as well as increased secretion during cell based production, as well as methods of utilizing such peptides. The peptide conjugates include a short peptide domain defined by the amino acid sequence AGIH (SEQ ID NO: 8) and may include a biologically active molecule useful in intracellular and intranuclear transport of the biologically active molecule to treat various disorders and diseases. |
申请公布号 |
WO2010138769(A1) |
申请公布日期 |
2010.12.02 |
申请号 |
WO2010US36482 |
申请日期 |
2010.05.27 |
申请人 |
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS;WEISBART, RICHARD, H. |
发明人 |
WEISBART, RICHARD, H. |
分类号 |
C07K16/46;A61K39/395;C12P21/08 |
主分类号 |
C07K16/46 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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