发明名称 POLYHYDROXYALKANOATE PRODUCTION BY COENZYME A-DEPENDENT ALDEHYDE DEHYDROGENASE PATHWAYS
摘要 <P>PROBLEM TO BE SOLVED: To provide methods for producing PHA polymers or copolymers that avoids increasing the level of 3-hydroxyacid in the feed. <P>SOLUTION: The method for PHA polymer production by coenzyme A-dependent aldehyde dehydrogenase pathways, includes expressing genes encoding one or more enzymes of acyl-CoA transferase, acyl-CoA synthetase, &beta;-ketothiolase, acetoacetyl-CoA reductase and/or PHA synthase, where at least one gene is a heterologous gene, and feeding an alcohol to the organism. At least one step in the conversion step involves a Co-enzyme A-dependent aldehyde dehydrogenase activity. <P>COPYRIGHT: (C)2011,JPO&INPIT
申请公布号 JP2010268797(A) 申请公布日期 2010.12.02
申请号 JP20100137010 申请日期 2010.06.16
申请人 METABOLIX INC 发明人 SKRALY FRANK A
分类号 C12P7/62;A01H5/00;A61K9/00;A61K9/48;A61K35/12;A61K49/00;A61L15/00;A61L17/00;A61L27/00;A61L31/00;C12N1/15;C12N1/19;C12N1/21;C12N9/02;C12N15/09;C12N15/52 主分类号 C12P7/62
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