摘要 |
<p>A cartridge in which sonication is applied to biological matter to disrupt and release nucleic acids from the matter is formed from a cartridge body containing a series of wells connected by fluid passages engineered to prevent backflow, with at least one well containing a sonication window covered by a thin lamina to transmit sonic vibrations from a sonication horn contacting the exterior surface of the window. Fluid transport among the wells is achieved by pressure differentials through the fluid passages, and a succession of functions is performed in the various wells, including disruption, mixing, binding of the released nucleic acids to binding materials, washing, elution, and collection.</p> |
申请人 |
BIO-RAD LABORATORIES, INC.;SADRI, AMIR M.;KIRCANSKI, NENAD;KIRCANSKI, MANJA;NIKOLIC, NEVEN;TIMOTIJEVIC, MILIJA |
发明人 |
SADRI, AMIR M.;KIRCANSKI, NENAD;KIRCANSKI, MANJA;NIKOLIC, NEVEN;TIMOTIJEVIC, MILIJA |