发明名称 |
GASTRIC RETENTION CONTROLLED DRUG DELIVERY SYSTEM |
摘要 |
The present invention provides a gastric retention controlled drug delivery system comprising: (a) a controlled release core comprising a drug, a highly swellable polymer and a gas generating agent, said core being capable of swelling and achieving floatation rapidly while maintaining its physical integrity in gastrointestinal fluids for prolonged periods, and (b) a rapidly releasing coat composition comprising the same drug as in the core and pharmaceutically acceptable excipients, wherein the coating composition surrounds the core such that the system provides a biphasic release of the drug in gastrointestinal fluids.
|
申请公布号 |
US2010305208(A1) |
申请公布日期 |
2010.12.02 |
申请号 |
US20100856097 |
申请日期 |
2010.08.13 |
申请人 |
SUN PHARMA ADVANCED RESEARCH COMPANY LTD. |
发明人 |
DUDHARA KAMLESH MAHANLAL;DHARMADHIKARI NITIN BHALACHANDRA;DHAVSE VAISHALI VIJAY |
分类号 |
A61K9/30;A61K31/195;A61K9/00;A61K9/22;A61K9/24;A61K9/46;A61K31/197;A61K47/04;A61K47/12;A61K47/32;A61K47/36;A61K47/38;A61P7/00;A61P9/10 |
主分类号 |
A61K9/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|