| 发明名称 |
INHIBITION 0F INFLAMMATION USING ANTAGONISTS OF MUC1 |
| 摘要 |
<p>The invention provides for peptides from the MUCl cytoplasmic domain and methods of use therefor. These peptides can inhibit MUCl oligomerization, inhibit the interaction of MUCl with NF -KB or a STAT, and block inflammatory response mediated by NF-?B or STAT signaling.</p> |
| 申请公布号 |
CA2763327(A1) |
申请公布日期 |
2010.12.02 |
| 申请号 |
CA20102763327 |
申请日期 |
2010.05.27 |
| 申请人 |
DANA-FARBER CANCER INSTITUTE, INC.;GENUS ONCOLOGY, LLC |
发明人 |
KUFE, DONALD W.;KHARBANDA, SURENDER |
| 分类号 |
C07K14/705;A61K38/09;A61K38/10;A61K38/17;A61P29/00;C07K7/08 |
主分类号 |
C07K14/705 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
