发明名称 SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS
摘要 The present invention provides a compound of formula (I') or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
申请公布号 CA2763565(A1) 申请公布日期 2010.12.02
申请号 CA20102763565 申请日期 2010.05.26
申请人 NOVARTIS AG 发明人 COPPOLA, GARY MARK;IWAKI, YUKI;KARKI, RAJESHRI GANESH;KAWANAMI, TOSHIO;KSANDER, GARY MICHAEL;MOGI, MUNETO;SUN, ROBERT
分类号 C07C233/45;A61K31/165;A61K31/166;C07C233/57;C07C233/64 主分类号 C07C233/45
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