发明名称 |
SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS |
摘要 |
The present invention provides a compound of formula (I') or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, X and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. |
申请公布号 |
CA2763565(A1) |
申请公布日期 |
2010.12.02 |
申请号 |
CA20102763565 |
申请日期 |
2010.05.26 |
申请人 |
NOVARTIS AG |
发明人 |
COPPOLA, GARY MARK;IWAKI, YUKI;KARKI, RAJESHRI GANESH;KAWANAMI, TOSHIO;KSANDER, GARY MICHAEL;MOGI, MUNETO;SUN, ROBERT |
分类号 |
C07C233/45;A61K31/165;A61K31/166;C07C233/57;C07C233/64 |
主分类号 |
C07C233/45 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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