发明名称 |
METHOD FOR PRODUCTION OF ORALLY RAPIDLY DISINTEGRATING TABLET COMPRISING IMIDAFENACIN AS ACTIVE INGREDIENT |
摘要 |
<p>The present invention herein provides an imidafenacin-containing orally rapidly disintegrating tablet which is excellent in the photostability. The present invention comprises the steps of: (A) granulating imidafenacin together with starch to thus give a granulated product having an imidafenacin concentration ranging from 0.001 to 3% by mass and a starch concentration ranging from 40 to 99.999% by mass; (B) covering the granulated product prepared in the step (A) with a non-cellulosic coating agent; and (C) blending the granulated product obtained in the preceding step (B) with an excipient and a disintegrating agent and then forming the resulting mixture into a tablet according to the compression molding technique.</p> |
申请公布号 |
KR20100126335(A) |
申请公布日期 |
2010.12.01 |
申请号 |
KR20107019209 |
申请日期 |
2009.01.30 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIZAKI TOSHIHIRO;AOKI YOSHINOBU |
分类号 |
A61K31/4164;A61K9/22;A61K47/32;A61P13/10 |
主分类号 |
A61K31/4164 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|