发明名称 ANTHRANILIC ACID AMIDES WITH A HETEROARYLSULFONYL SIDE CHAIN, METHOD FOR THE PRODUCTION THEREOF, USE THEREOF AS A MEDICAMENT OR A DIAGNOSTIC AGENT AND PHARMACEUTICAL PREPARATIONS CONTAINING SAID COMPOUNDS
摘要 The invention relates to compounds of formula (I), wherein R(1) -R(7) have the meanings cited in the claims. Said compounds act upon the Kv1.5-potassium channel and inhibit a potassium flow in the atrium of the human heart, designated as an ultra-rapidly activating delayed rectifier. As a result, they are particularly suitable for use as novel antiarrhythmic active substances, especially in the treatment and prophylaxis of atrial arrhythmia, e.g. atrial fibrillation (AF) or atrial flutter.
申请公布号 CA2450076(C) 申请公布日期 2010.11.30
申请号 CA20022450076 申请日期 2002.05.31
申请人 AVENTIS PHARMA DEUTSCHLAND GMBH 发明人 BRENDEL, JOACHIM;BOEHME, THOMAS;PEUKERT, STEFAN;KLEEMANN, HEINZ-WERNER
分类号 C07D215/36;A61K31/33;A61K31/42;A61K31/4245;A61K31/4402;A61K31/47;A61K31/472;A61K31/497;A61K45/06;A61P9/06;C07D213/70;C07D213/71;C07D217/02;C07D261/10;C07D271/12;C07D333/34;C07D401/12;C07D405/12 主分类号 C07D215/36
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