发明名称 |
SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVES AND USE THEREOF |
摘要 |
A compound represented by the formula (I) or a salt thereof: (see formula I) wherein n represents an integer of 1 to 3, R represents an alkyl group having 3 to 8 carbon atoms, a group represented by the following formula: R1(CH2)k- (wherein k represents 0 or an integer of 1 to 3; R1 represents a saturated cyclic alkyl group having 3 to 7 carbon atoms or a saturated condensed cyclic alkyl group having 6 to 8 carbon atoms, and the group R1 may be substituted with a lower alkyl group having 1 to 4 carbon atoms) and the like, and Ar represents a condensed bicyclic group such as naphthalen-1-yl group, which has suppressing action on prostaglandin and leukotriene production and is useful for prophylactic and/or therapeutic treatment of various inflammatory diseases and the like caused by these lipid mediators.
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申请公布号 |
CA2477208(C) |
申请公布日期 |
2010.11.30 |
申请号 |
CA20032477208 |
申请日期 |
2003.02.20 |
申请人 |
ASAHI KASEI PHARMA CORPORATION |
发明人 |
SHODA, MOTOSHI;KURIYAMA, HIROSHI |
分类号 |
C07C69/734;A61K31/192;A61K31/216;A61K31/235;A61K31/255;A61K31/341;A61K31/381;A61K31/404;A61K31/421;A61K31/428;A61K31/4353;A61K31/44;A61K31/4402;A61K31/4406;A61K31/47;A61P25/04;A61P29/00;A61P37/02;A61P37/08;A61P43/00;C07C59/58;C07C59/62;C07C59/68;C07C59/72;C07C205/56;C07C229/42;C07C233/54;C07C235/06;C07C235/16;C07C235/20;C07C237/20;C07C275/42;C07C307/10;C07C311/08;C07C311/29;C07C317/46;C07D209/08;C07D209/12;C07D209/18;C07D213/30;C07D215/14;C07D215/22;C07D217/02;C07D217/24;C07D231/12;C07D263/32;C07D277/62;C07D277/68;C07D277/72;C07D277/82;C07D307/42;C07D307/68;C07D307/79;C07D333/54;C07D409/12 |
主分类号 |
C07C69/734 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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