发明名称 |
4−PYRIMIDINYL−N−ACYL−L−PHENYLALANINES |
摘要 |
Coumpounds of Formula (I) are disclosed, wherein R<1> to R<6> are as defined in specification and which are inhibitors of binding between VCAM-1 and cells expressing VLA-4, and accordingly are useful for treating diseases whose symptoms and or damage are related to the binding of VCAM-1 to cells expressing VLA-4. |
申请公布号 |
PL207160(B1) |
申请公布日期 |
2010.11.30 |
申请号 |
PL20000357601 |
申请日期 |
2000.11.28 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
SIDDURI ACHYUTHARAO;TILLEY JEFFERSON WRIGHT |
分类号 |
C07D239/06;A61K9/14;A61K31/505;A61K31/513;A61K38/00;A61P1/04;A61P11/06;A61P19/02;A61P25/00;A61P29/00;C07D239/54;C07K5/078 |
主分类号 |
C07D239/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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