发明名称 METHOD FOR THE PRODUCTION OF 4-(6-BROMOHEXYLOXY) BUTYLBENZENE
摘要 The invention relates to an improved method for producing 4-(6-bromohexyloxy) butylbenzene by reacting 4-phenylbutanol with 1,6-dibromohexane in the presence of a base and a phase transfer catalyst. 4-phenylbutanol is metered in a diluent to a mixture consisting of 1,6-dibromohexane, a base, a phase transfer catalyst, and a diluent. Also disclosed is the use of the resulting 4-(6-bromohexyloxy) butylbenzene for producing salmeterol in a previously known manner.
申请公布号 IL163698(A) 申请公布日期 2010.11.30
申请号 IL20040163698 申请日期 2004.08.24
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG 发明人
分类号 C07B61/00;C07C41/16;C07C43/174 主分类号 C07B61/00
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