发明名称 PYRROLO [2,3 - D] PYRIMIDIN DERIVATIVES AS PROTEIN KINASE B INHIBITORS
摘要 wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising said compounds, methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).
申请公布号 IL204721(D0) 申请公布日期 2010.11.30
申请号 IL20100204721 申请日期 2010.03.25
申请人 ASTRAZENECA AB;PAUL, DAVID JOHNSON;ANDREW LEACH;RICHARD, WILLIAM, ARTHUR LUKE;ZBIGNIEW STANLEY MATUSIAK;JEFFREY JAMES MORRIS 发明人
分类号 C07D 主分类号 C07D
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