发明名称 POLYNUCLEOTIDE SEQUENCES TO A STREPTOMYCES AVERMITILIS aveC ALLELE PRODUCING A REDUCED CLASS 2:1 RATIO OF AVERMECTINS
摘要 The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of class 2:1 avermectins produced in fermentation cultures of S. avermitilis. The present invention further relates to vectors, host cells, and mutant strains of S. avermitilis in which the ave C gene has been inactivated, or mutated so as to change the ratio or amount of class 2:1 avermectins produced.
申请公布号 IL192371(A) 申请公布日期 2010.11.30
申请号 IL20080192371 申请日期 2008.06.22
申请人 PFIZER PRODUCTS, INC. 发明人
分类号 C12N15/09;A61K31/7048;A61P33/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/88;C12N15/11;C12N15/31;C12N15/60;C12P17/18;C12P19/62;C12R1/465 主分类号 C12N15/09
代理机构 代理人
主权项
地址