Disclosed is an antibody binding to P-selectin, not binding to complement factor Clq and not to Fcg receptors and that contains an Fc part derived from human origin. Further disclosed is the use of said antibody for the preparation of a medicament for the prophylaxis or treatment of inflammatory and thrombotic disorders, including critical limb ischemia and peripheral arterial occlusive disease. (62) Divided Out of 549872
