发明名称 |
ISOLATED PEPTIDES AND USES THEREOF |
摘要 |
The present invention provides isolated preproinsulin-derived peptides of 8 or 9 amino acids, comprising the amino acid sequence WGPDPAA (SEQ ID NO: 1), isolated Class I peptide-HLA complexes presenting said peptides and isolated molecules having binding affinity for said peptides and/or said peptide-HLA complexes. Such compositions are useful in the treatment of Type 1 diabetes mellitus (T1DM).
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申请公布号 |
US2010297011(A1) |
申请公布日期 |
2010.11.25 |
申请号 |
US20080666416 |
申请日期 |
2008.06.27 |
申请人 |
KING'S COLLEGE LONDON |
发明人 |
PEAKMAN MARK;CALVINO RUBEN VARELA |
分类号 |
A61K49/00;A61K31/7088;A61K38/17;A61K38/28;A61K39/395;A61P3/10;C07H21/00;C07K14/00;C07K14/725;C07K16/00;C07K16/18;C12N1/21;C12N15/63;G01N33/50;G01N33/53 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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