发明名称 |
DUAL AND SINGLE LAYER DOSAGE FORMS |
摘要 |
Provided is a dual-release, dual-adhesiveness flexible thin film dosage form comprising: a quick-release subfilm comprising an admixture of polymer, which comprises predominantly highly water-soluble polymer(s), and a bioactive agent, the polymers and other components of the quick-release subfilm adapted to provide 20 minute or less erodibility for the quick-release subfilm; and laminated against the quick-release subfilm, a sustained-release subfilm comprising an admixture of polymer, which comprises predominantly hydrophilic, bioadhesive polymer(s), and a second bioactive agent, which can be the same as the first, the polymers and other components of the sustained-release subfilm adapted to provide erodibility of 1 hours or more and 20 hours or less for the sustained-release subfilm, the dosage form having a thickness of 30 mil or less, and being more adhesive on the sustained-release side. |
申请公布号 |
WO2010135053(A2) |
申请公布日期 |
2010.11.25 |
申请号 |
WO2010US31991 |
申请日期 |
2010.04.22 |
申请人 |
BIONEX PHARMACEUTICALS LLC;TAN, HOCK, SENG;CHUNG, SIEW, LIAN |
发明人 |
TAN, HOCK, SENG;CHUNG, SIEW, LIAN |
分类号 |
A61F13/02;A61K9/70;A61L15/22;A61L15/44;A61M35/00 |
主分类号 |
A61F13/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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