发明名称 Endothelin Single Nucleotide Polymorphisms and Methods of Predicting B-Adrenergic Receptor Targeting Agent Efficacy
摘要 The present invention concerns the use of methods for evaluating &bgr;-adrenergic receptor targeting agent treatment for a patient, particularly one with a heart condition. In general, the disclosed methods entail determining the presence or absence of one or more polymorphisms in an endothelin gene system member. Based on the results of this determination, a &bgr;-adrenergic receptor targeting agent may be prescribed, administered or a treatment regimen altered, including the administration of a &bgr;-blocker. Accordingly, methods of treatment are also described.
申请公布号 US2010298399(A1) 申请公布日期 2010.11.25
申请号 US20080670966 申请日期 2008.07.28
申请人 TAYLOR MATTHEW R G;MESTRONI LUISA 发明人 TAYLOR MATTHEW R. G.;MESTRONI LUISA
分类号 A61K31/403;A61K31/138;A61K31/164;A61K31/167;A61K31/4035;A61P9/00;A61P9/04;C12Q1/68;G01N33/50 主分类号 A61K31/403
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