| 发明名称 |
2-BIPHENYLAMINO-4-AMINOPYRIMIDINE DERIVATIVES AS KINASE INHIBITORS |
| 摘要 |
The invention provides novel pyrimidine derivatives of formula (1) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or anaplastic lymphoma kinase (ALK).
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| 申请公布号 |
US2010298295(A1) |
申请公布日期 |
2010.11.25 |
| 申请号 |
US20080675379 |
申请日期 |
2008.08.27 |
| 申请人 |
IRM LLC |
发明人 |
MARSILJE THOMAS H.;LU WENSHUO;CHEN BEI;HE XIAOHUI;BURSULAYA BADRY;LEE CHRISTIAN CHO-HUA;GRAY NATHANAEL S. |
| 分类号 |
A61K31/55;A61K31/505;A61K31/506;A61K31/5377;A61P31/00;A61P35/00;A61P37/06;C07D239/48;C07D401/12;C07D403/12;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C12N5/02 |
主分类号 |
A61K31/55 |
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