发明名称 |
3-[4-(7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-1H-PYRAZOL-1-YL]OCTANE- OR HEPTANE-NITRILE AS JAK INHIBITORS |
摘要 |
The present invention relates to the Janus kinase (JAK) inhibitors 3-[4-(7H-pyrrolo[2,3- d]pyrimidin-4-yl)-1H-pyrazol-l-yl]octanenitrile or 3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-y1)-1H- pyrazol-l-yl]heptanenitrile, as well as its compositions and methods of use, which is useful in the treatment of JAK-associated diseases including, for example, inflammatory and autoimmune disorders, skin disorders, cancer, and other diseases. |
申请公布号 |
WO2010135621(A1) |
申请公布日期 |
2010.11.25 |
申请号 |
WO2010US35728 |
申请日期 |
2010.05.21 |
申请人 |
INCYTE CORPORATION;LI, YUN-LONG;RODGERS, JAMES D. |
发明人 |
LI, YUN-LONG;RODGERS, JAMES D. |
分类号 |
A61K31/519;A61P17/00;A61P27/02;A61P29/00;A61P35/00;C07D487/04 |
主分类号 |
A61K31/519 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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