摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a mammalian cell and a method for the enhanced expression of a secreted, recombinant protein in mammalian host cells, and a reagent for the method. <P>SOLUTION: There is disclosed a method for enhancing the production volume of a secreted, recombinant protein product by introducing a molecular chaperone into mammalian host cells. There is also disclosed a mammalian host cell with enhanced expression of a secreted, recombinant protein by coexpressing at least one chaperone protein. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |