摘要 |
PROBLEM TO BE SOLVED: To provide an immune sensor with a monoclonal antibody having selective binding capacity to a target organic nitrate-based explosive as the probe, and to provide a method of manufacturing the same. SOLUTION: As an antibody having binding capacity to an organic nitrate-based explosive which does not exhibit immunogenicity, an antibody having cross reactivity to the organic nitrate-based explosives is selected from a group of antibodies to low-molecular compounds having a structure similar to a structure characteristic of the organic-nitrate explosive. The antibody having the cross reactivity is immobilized to a transducer to form the immune sensor. COPYRIGHT: (C)2011,JPO&INPIT
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