发明名称 |
1-Amino-alkyl-cyclohexanes as 5-HT3 and neuronal nicotinic receptor antagonists |
摘要 |
Certain 1-aminoalkylcyclohexanes are systematically-active 5HT3 and nicotinic receptor antagonists and are useful in the inhibition of progression of or alleviation of conditions resulting from disturbances of serotoninergic or nicotinergic transmission giving them a wide range of utility in the treatment of CNS-disorders. Pharmaceutical compositions thereof for such purpose and method of making same, as well as a method-of-treating conditions which are alleviated by the employment of a 5HT3 or neuronal nicotinic receptor antagonist. |
申请公布号 |
US2010298442(A1) |
申请公布日期 |
2010.11.25 |
申请号 |
US20100804610 |
申请日期 |
2010.07.26 |
申请人 |
MERZ PHARMA GMBH & CO. KGAA |
发明人 |
PARSONS CHRISTOPHER GRAHAM RAPHAEL;DANYSZ WOJCIECH;GOLD MARKUS;KALVINSH IVARS;KAUSS VALERJANS;JIRGENSONS AIGARS |
分类号 |
A61K31/13;C07D295/02;A61K31/40;A61P1/00;A61P1/08;A61P3/00;A61P25/00;A61P25/04;A61P25/06;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P25/32;A61P29/00;A61P43/00;C07C211/35 |
主分类号 |
A61K31/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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