| 摘要 |
<p>Disclosed are an immunosensor whereby an explosive of the peroxide derivative type to be detected can be detected through an antigen-antibody reaction using a newly constructed antibody capable of binding to the explosive of the peroxide derivative type to be detected, and a method for producing the immunosensor. As the antibody capable of binding to the explosive of the peroxide derivative type to be detected, for example, triacetone triperoxide, a monoclonal antibody showing cross reactivity with the aforesaid explosive of the peroxide derivative type is selected from among monoclonal antibodies against 3-[12-(2-carboxyethyl)-9,12-dimethyl-7,8,10,11,13,14-hexaoxa-spiro-[5.8]tetradec-9-yl]-propionic acid which has a structure similar to the aforesaid peroxide derivative. Then, an immunosensor, whereby the peroxide derivative to be detected is selectively detected through an antigen-antibody reaction, is produced.</p> |
