METHOD FOR DETECTION OF FREE NUCLEIC ACID IN BLOOD

摘要

Disclosed is an analysis method in which the influence of a free nucleic acid that is irrelevant to a disease such as a tumor or the like can be eliminated to measure only the blood level of an exactly desired free nucleic acid (which has been employed as a diagnostic marker for the disease) as accurately as possible in the measurement of the blood level of the desired free nucleic acid. Specifically disclosed is a method for analyzing a free blood nucleic acid contained in a blood-derived sample, which is characterized by comprising a step of removing platelet-derived microvesicles from a plasma or serum sample (i.e., the blood-derived sample). Preferably, the platelet-derived microvesicles in the blood-derived sample are removed using an antibody capable of binding to epitopes existing specifically on the surfaces of the microvesicles.