| 发明名称 |
Polypeptide biomarkers for diagnosing Alzheimer's disease |
| 摘要 |
<p>A method for assessing the state of Alzheimer's disease in patients is disclosed. A method for monitoring the progression of Alzheimer's disease in patients is also disclosed. The method applies detection of specific markers in body fluids (e.g. CSF), using mass spectrometric analysis (SELDI-TOF MS). The specific markers are: human cystatin C, human beta-2-microglobulin, human myoglobin neurosecretory protein VGF or fragments of these proteins.</p> |
| 申请公布号 |
EP2221620(A3) |
申请公布日期 |
2010.11.24 |
| 申请号 |
EP20100164475 |
申请日期 |
2003.08.11 |
| 申请人 |
BAYER SCHERING PHARMA AG |
发明人 |
YALKINOGLU, OEZKAN, DR.;KOENIG, GERHARD, DR.;HOCHSTRASSER, DENIS FRANCOIS, PROF.DR.;SANCHEZ, JEAN-CHARLES, DR.;CARETTE, ODILE, DR. |
| 分类号 |
G01N27/62;G01N33/68;C07K14/47;C07K14/74;C07K14/805;C07K14/81;C12Q1/37;G01N33/53 |
主分类号 |
G01N27/62 |
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