| 摘要 |
There is provided a neuronal cell death inhibitor having a high efficacy. A neuronal cell death inhibitor comprising a compound of general formula (1) below:
(where R 1 is a hydrogen atom or an optionally substituted hydroxy group; R 2 is a hydrogen atom; R 3 is a hydrogen atom or an optionally substituted hydroxy group; R 4 is a hydrogen atom or an optionally substituted hydroxy group, R 3 together with R 4 is optionally an oxo group or a group of -O-(CH 2 ) n -O- (where n is an integer of 2 to 4), or R 7 together with R 4 optionally forms an unsaturated bond between carbon atoms, the respective carbon atoms being attached to R 2 and R 4 ; R 5 is a hydrogen atom or an optionally substituted lower alkyl group; each of R 6 , R 7 , and R 8 is the same as or different from each other and is a hydrogen atom, an optionally substituted hydroxy group, an optionally substituted alkyl group, an optionally substituted aryl group, or an optionally substituted heteroaryl group); or a salt thereof.
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