TEMPLATED OPEN FLOCS OF ANISOTROPIC PARTICLES FOR ENHANCED PULMONARY DELIVERY
摘要
The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery.
申请公布号
EP2252275(A2)
申请公布日期
2010.11.24
申请号
EP20090709833
申请日期
2009.02.13
申请人
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
发明人
JOHNSTON, KEITH, P.;ENGSTROM, JOSHUA;TAM, JASMINE;WILLIAMS, III, ROBERT, O.