发明名称 |
WEST NILE VIRUS VACCINE, AND METHOD FOR PRODUCTION THEREOF |
摘要 |
The present invention provides virus-like particles (VLP) highly secreting or producing signal peptide obtained by altering a signal sequence derived from West Nile virus (WNV), the signal peptide, a WNV VLP secretion expression vector containing a nucleic acid encoding prM protein and E protein, a WNP VLP highly secreting or producing animal cell line harboring the vector, a WNV vaccine containing WNV VLP obtained by the cell line as an active ingredient, and a WNV DNA vaccine containing the ALP secretion expression vector as an active ingredient. |
申请公布号 |
EP2221368(A4) |
申请公布日期 |
2010.11.24 |
申请号 |
EP20080846317 |
申请日期 |
2008.11.07 |
申请人 |
JAPAN AS REPRESENTED BY DIRECTOR GENERAL OF NATIONAL INSTITUTE OF INFECTIOUS DISEASES;THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OFOSAKA UNIVERSITY |
发明人 |
KOJIMA, ASATO;TAKAHASHI, HIDEHIRO;ISHIKAWA, TOYOKAZU |
分类号 |
C12N15/09;A61K39/12;A61P31/12;C07K14/18;C12N5/10 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|