| 摘要 |
Provided is an aptamer that can bind to histidine peptide. A nucleic acid (a), (b), (c) or (d) below is used as an aptamer that can bind to histidine peptide. (a) A a nucleic acid containing a base sequence represented by GGUNnAYUmGGH. Here, N represents A, G, C, U or T, the n of Nn is the number of N and is an integer from 1 to 3, Y represents U, T or C, the m of Um is the number of U, and is an integer from 1 to 3, and H represents U, T, C, or A. (b) A nucleic acid containing a base sequence obtained by substituting, deleting, adding or inserting one or more bases to the base sequence (a), and which is capable of bonding to the aforementioned histidine peptide. (c) A nucleic acid containing a base sequence represented by GGCGCCUUCGUGGAAUGUC. (d) A nucleic acid containing a base sequence obtained by substituting, deleting, adding or inserting one or more bases to the base sequence (c), and which is capable of bonding to the aforementioned histidine peptide. |
