发明名称 |
METHOD AND REAGENTS FOR TREATING HEPATIC FIBROSIS AND INFLAMMATION |
摘要 |
The invention relates to methods for identifying an anti-fibrotic or anti-inflammatory agent comprising determining cathepsin S expression in activated hepatic stellate cells which have been exposed to a test compound and comparing expression to non-exposed hepatic stellate cells. The invention also relates to methods for treating a disorder characterised or caused by hepatic fibrosis or inflammation, comprising administering a cathepsin S inhibitor to a subject. |
申请公布号 |
US2010292298(A1) |
申请公布日期 |
2010.11.18 |
申请号 |
US20070279984 |
申请日期 |
2007.04.23 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
MAUBACH GUNTER;ZHUO LANG;LIM MICHELLE CHIN CHIA |
分类号 |
A61K31/713;A61K31/336;A61K31/4545;A61K31/5375;A61P29/00;G01N33/573 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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