发明名称 Site-Specific Inhibitors of Histone Methyltransferase [HMTASE] and Process of Preparation Thereof
摘要 The present invention relates to compounds of structural formula (I) as site-specific inhibitor of histone methyl-transferase, where R1 and R1 is —OCH or —OH, R2 and R2 is —OH or —OAc; a process of isolating compound of structural formula (Ia), where R1 and R1 is —OCH, R2 and R2 is —OH; a process of preparation of compound of structural formula (Ib), where R1 and R1 is —OCH, R2 and R2 is —OAc; a process of preparation of compound of structural formula Ic, where R1 and R1 is —OH, R2 and R2 is —OH; and use of compounds of structural formula I for manufacture of a medicament for management of cancer and/or disease conditions in a subject in need thereof.
申请公布号 US2010292498(A1) 申请公布日期 2010.11.18
申请号 US20070306675 申请日期 2007.06.26
申请人 JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH 发明人 KUNDU TAPAS KUMAR;VIKRU RUTHROTHA SELVI BHARATHA;ANNAVARAPU HARI KISHORE;KEMPEGOWDA MATELINGU
分类号 C07C69/76;C07C63/331 主分类号 C07C69/76
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