TREATMENT OF IL-25 MEDIATED DISEASES WITH TLR ANTAGONISTS

摘要

The invention provides methods and compositions for use in treating or preventing an IL-25 mediated disease such as asthma. The methods and compositions involve using TLRl or TLR2 antagonists, such as antibody molecules which bind TLRl or TLR2, or soluble TLRl or TLR2 receptors. The invention also provides methods of screening for antagonists of TLRl or TLR2.