发明名称 |
COMBINATION OF A PHOSPHOINOSITIDE 3-KINASE INHIBITOR AND AN ANTIDIABETIC COMPOUND |
摘要 |
The invention relates to a pharmaceutical combination which comprises (a) a phosphosnositide 3-kinase inhibitor compound and (b) an insulin sensitivity enhancer compound for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human.
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申请公布号 |
CA2760179(A1) |
申请公布日期 |
2010.11.18 |
申请号 |
CA20102760179 |
申请日期 |
2010.05.12 |
申请人 |
NOVARTIS AG |
发明人 |
BASELGA, JOSE;DI COSIMO, SERENA;GARCIA-ECHEVERRIA, CARLOS;HACKL, WOLFGANG;MAIRA, SAUVEUR-MICHEL;RUSSILLO, MICHELANGELO;SERRA ELIZALDE, VIOLETA |
分类号 |
A61K31/155;A61K31/426;A61K31/427;A61K31/437;A61K31/4439;A61K31/496;A61K31/5377;A61K45/06;A61P3/10;A61P35/00 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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