| 发明名称 |
TARGETING OF RNA WITH EXTERNAL GUIDE SEQUENCES |
| 摘要 |
The present disclosure provides compositions and methods for modulating gene expression by using EGS to target miRNA. Another aspect of the present disclosure is the use of EGS to target mitochondrial RNA. MiRNA targets may include immature or mature forms of miRNA, such as miRNA overexpressed in diseases such as cancer.
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| 申请公布号 |
US2010292099(A1) |
申请公布日期 |
2010.11.18 |
| 申请号 |
US20080671498 |
申请日期 |
2008.08.22 |
| 申请人 |
KEREN PHARMACEUTICAL, INC. |
发明人 |
DREYFUS DAVID H.;GHODA LUCY Y. |
| 分类号 |
C40B30/06;C07H21/00;C12N1/21;C12N5/10;C12N15/63;C12N15/64;C40B40/08 |
主分类号 |
C40B30/06 |
| 代理机构 |
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