发明名称 |
NOVEL DIAGNOSTIC MARKER FOR TYPE 1 DIABETES MELLITUS |
摘要 |
The present invention relates to a novel diagnostic marker for type 1 diabetes mellitus, and more specifically to a diagnostic composition for type 1 diabetes mellitus containing aminoacyl-tRNA synthetase or an antibody therefor as an effective component, application of the aminoacyl-tRNA synthetase in the preparation of a diagnostic agent for type 1 diabetes mellitus, and a diagnosis method for type 1 diabetes mellitus that involves the detection of anti-Alanine tRNA synthetase antibodies, anti-Glycine tRNA synthetase antibodies, anti-Asparagine tRNA synthetase antibodies and anti-Tryptophan tRNA synthetase antibodies from a sample of an object. The composition, diagnosis kit and diagnosis method of the present invention facilitate the diagnosis of type 1 diabetes mellitus from the specimen of a patient, and thus may be used for early diagnosis and confirmation of type 1 diabetes mellitus. |
申请公布号 |
WO2010090471(A3) |
申请公布日期 |
2010.11.18 |
申请号 |
WO2010KR00710 |
申请日期 |
2010.02.05 |
申请人 |
SEOUL NATIONAL UNIVERSITY HOSPITAL;SNU R&DB FOUNDATION;PARK, SANG GYU;PARK, KYONG SOO;KIM, SUNGHOON |
发明人 |
PARK, SANG GYU;PARK, KYONG SOO;KIM, SUNGHOON |
分类号 |
C12Q1/25;G01N33/53 |
主分类号 |
C12Q1/25 |
代理机构 |
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主权项 |
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