发明名称 |
COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF GLUCOCORTICOID RECEPTOR (GCR) GENES |
摘要 |
This invention relates to a double-stranded ribonucleic acid (ds RNA) for inhibiting the expression of a GCR gene. The invention also relates to a pharmaceutical composition comprising the ds RNA or nucleic acid molecules or vectors encoding the same together with a pharmaceutically acceptable carrier; methods for treating diseases caused by the expression of a GCR gene using said pharmaceutical composition; and methods for inhibiting the expression of GCR in a cell.
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申请公布号 |
CA2759838(A1) |
申请公布日期 |
2010.11.18 |
申请号 |
CA20102759838 |
申请日期 |
2010.05.12 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BAILLY, JACQUES;BENARDEAU, AGNES;BRAMLAGE, BIRGIT;CONSTIEN, RAINER;FORST, ANDREA;HOSSBACH, MARKUS;SCHOTT, BRIGITTE |
分类号 |
C12N15/113;A61K31/713;C07H21/02;C07K14/72 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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