发明名称 ANTI-AXL ANTIBODY
摘要 <p>By humanizing an anti-AXL antibody originating from mouse, the immunogenicity thereof in humans can be reduced. Provided are an antibody capable of binding to a specific region in Anexelekto (AXL); and a humanized antibody constructed on the basis of this antibody. The aforesaid anti-AXL antibody has a high antitumor activity and, therefore, is useful as an agent for reducing the expression amount of AXL, an anticancer drug and a cancer diagnostic.</p>
申请公布号 CA2761891(A1) 申请公布日期 2010.11.18
申请号 CA20102761891 申请日期 2010.05.14
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 MAEDA, ATSUHIKO;MIYAMOTO, HAJIME;KURAMOCHI, TAICHI;MATSUO, ATSUSHI;IGAWA, TOMOYUKI;SHIRAIWA, HIROTAKE;TSUNODA, HIROYUKI;TACHIBANA, TATSUHIKO
分类号 C07K16/28;A61K39/395;A61P35/00;C07K16/46 主分类号 C07K16/28
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