| 发明名称 |
Method for the purification of entacapone |
| 摘要 |
<p>The present invention relates to a method for the purification of Entacapone in the crude form as obtained by a synthesis process. In particular, the present invention relates to a method for the purification of crude Entacapone, comprising crystallizing the said crude Entacapone from a mixture of solvents composed of toluene and acetone, wherein trans-Entacapone is isolated with a purity of more than 99.5% as determined by HPLC.</p> |
| 申请公布号 |
EP2251323(A1) |
申请公布日期 |
2010.11.17 |
| 申请号 |
EP20090160276 |
申请日期 |
2009.05.14 |
| 申请人 |
F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. |
发明人 |
GRANDINI, CRISTIANO;LEGANZA, ALESSANDRO;GALVAGNI, MARCO;PERUFFO, MASSIMO |
| 分类号 |
C07C253/34;C07C255/57 |
主分类号 |
C07C253/34 |
| 代理机构 |
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代理人 |
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| 主权项 |
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