发明名称 USE OF ELECTROSPUN MICROTUBES FOR DRUG DELIVERY
摘要 A method of attaching a cell or a membrane-coated particle-of-interest to a microtube is provided. The method comprising: co-electrospinning two polymeric solutions through co-axial capillaries, wherein a first polymeric solution of the two polymeric solutions is for forming a shell of the microtube and a second polymeric solution of the two polymeric solutions is for forming a coat over an internal surface of the shell, the first polymeric solution is selected solidifying faster than the second polymeric solution and a solvent of the second polymeric solution is selected incapable of dissolving the first polymeric solution and wherein the second polymeric solution comprises the cell or the membrane-coated particle-of-interest, thereby attaching the cell or the membrane-coated panicle-of-interest to the microtube. Also provided are microtubes with attached, entrapped or encapsulated cells or membrane-coated particles and methods of using same.
申请公布号 EP2250302(A2) 申请公布日期 2010.11.17
申请号 EP20090712148 申请日期 2009.02.12
申请人 TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. 发明人 ZUSSMAN, EYAL
分类号 D01D5/00;A61K9/70;A61M5/142;D01D5/34;D01F1/10 主分类号 D01D5/00
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