发明名称 KIT FOR DETECTING CANCER CELLS METASTASIZING INTO SENTINEL LYMPH NODE
摘要 <p>Provided is a simple kit by which carcinoma cells metastasizing from a primary cancer lesion to a lymph node, in particular, a sentinel lymph node can be conveniently and accurately detected within a short period of time. Also disclosed is a drug delivery agent whereby a drug to be used in a test or therapy can be preferentially delivered into the sentinel lymph node as described above in which an environment easily allowing the adhesion of micro cancer cells has been constructed by a primary cancer lesion and to which micro cancer cells adhere. A kit for detecting cancer cells metastasizing into a sentinel lymph node which comprises a human lymph channel-origin endothelial cell line attached to a base material. A drug delivery agent toward to sentinel lymph node wherein an antibody against an adhesive molecule, which mediates the adhesion of metastatic cancer cells from a primary cancer lesion to lymph channel endothelial cells in the sentinel lymph node, is exposed on the surface of colloidal particles.</p>
申请公布号 EP2251694(A1) 申请公布日期 2010.11.17
申请号 EP20090722615 申请日期 2009.01.28
申请人 SHINSHU UNIVERSITY 发明人 OHHASHI, TOSHIO;KAWAI, YOSHIKO
分类号 G01N33/574;A61K47/42;A61K49/04;A61K49/18;C12Q1/04 主分类号 G01N33/574
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