发明名称 |
LIPOSOMAL COMPOSITION COMPRISING WATER-SOLUBLE CORTICOSTEROIDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS |
摘要 |
A pharmaceutical composition for parenteral administration, comprising liposomes composed of non-charged vesicle-forming lipids, including up to 20 mole percent of an amphipathic vesicle-forming lipid derivatised with polyethyleneglycol, and optionally including not more than 10 mole percent of negatively charged vesicle-forming lipids, the liposomes having a selected mean particle diameter in the size range between about 40-200 nm and containing a water soluble corticosteroid for the site-specific treatment of inflammatory disorders, is provided.
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申请公布号 |
CA2430897(C) |
申请公布日期 |
2010.11.16 |
申请号 |
CA20012430897 |
申请日期 |
2001.12.07 |
申请人 |
UNIVERSITEIT UTRECHT HOLDING B.V. |
发明人 |
METSELAAR, JOSBERT MAARTEN;WAUBEN, MARCA HENRIETTE MICHAELA;STORM, GERRIT |
分类号 |
A61K9/127;A61K31/573;A61K31/58;A61K47/18;A61K47/34;A61K47/46;A61P25/00;A61P29/00 |
主分类号 |
A61K9/127 |
代理机构 |
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