发明名称 DIVALENT HYDRAZIDE COMPOUND CONJUGATES FOR INHIBITING CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR.
摘要 <p>Provided herein are divalent hydrazide-polyethylene glycol conjugates that inhibit the ion transport activity of a cystic fibrosis transmembrane conductance regulator (CFTR). The conjugates described herein are useful for treating diseases, disorders, and sequelae of diseases, disorders, and conditions that are associated with aberrantly increased CFTR activity, for example, secretory diarrhea.</p>
申请公布号 MX2010010783(A) 申请公布日期 2010.11.12
申请号 MX20100010783 申请日期 2009.04.03
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA. 发明人 ALAN S. VERKMAN;NITIN D. SONAWANE
分类号 C07C243/00;A61K31/165 主分类号 C07C243/00
代理机构 代理人
主权项
地址