Methods for treating autophagy-related disorders with agents which modulate expression of the gene encoding tyrosine phosphatase receptor type sigma (PTPRS) or which modulate the biological activity of the PTPRS gene product (PTPsigma). Methods for modulating autophagy in a cell with agents which modulate expression of PTPRS or which modulate the biological activity of PTPsigma; and related diagnostic methods, screening methods, and agents.
申请公布号
WO2010129681(A1)
申请公布日期
2010.11.11
申请号
WO2010US33740
申请日期
2010.05.05
申请人
VAN ANDEL RESEARCH INSTITUTE;MACKEIGAN, JEFFREY PAUL;MARTIN, KATIE R.;XU, HUAQIANG ERIC;XU, YONG