发明名称 REACTIVE HETEROCYCLE-SUBSTITUTED 7-HYDROXYCOUMARIN AND CONJUGATE THEREOF
摘要 <p><P>PROBLEM TO BE SOLVED: To provide fluorescent chemical materials comprising reactive dyes and dye conjugates and uses thereof. <P>SOLUTION: There are provided chemically active, water-soluble, heterocycle-substituted 7-hydroxycoumarin dyes, bioconjugates thereof and uses thereof. The conjugates obtained from the reactive heterocycle-substituted 7-hydroxycoumarin dyes are used for analyzing biological compounds by using a flow cytometer equipped with a violet laser as an excitation source due to their strong absorption at 405 nm and a high fluorescence quantum yield, and are particularly useful as fluorescent labels for reagents detecting biopolymers such as antibodies or nucleic acid probes. <P>COPYRIGHT: (C)2011,JPO&INPIT</p>
申请公布号 JP2010254993(A) 申请公布日期 2010.11.11
申请号 JP20100085260 申请日期 2010.04.01
申请人 BECTON DICKINSON & CO 发明人 DIWU ZHENJUN;DUBROVSKY TIMOTHY;ABRAMS BARNABY;LIAO JINFANG;MENG QINGLIN
分类号 C09B57/02;C07D407/04;C07D407/14;C07D409/04;C07D409/14;C07D417/04;C07D417/14;G01N33/533 主分类号 C09B57/02
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