发明名称 |
PREPATATION METHOD OF RIVASTIGMINE, ITS INTERMEDIATES AND PREPARATION METHOD OF THE INTERMEDIATES |
摘要 |
The present invention provides N-methylethylcarbamino-3-[(S)-1-(methyl-[(S)-1-phenylethyl]amino)ethyl]phenyl ester represented by formula (II) and its preparation method. The present invention also provides (S)-1-(3-methoxyphenyl)-N-methyl-N—[(S)-1-phenylethyl]ethylamine and 3-[(S)-1-(methyl-[(S)-1-phenylethyl]amino)ethyl]phenol as intermediates of the compound represented by formula (II), and the use of the compound represented by formula (II) for preparing rivastigmine used for treating Alzheimer disease.
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申请公布号 |
US2010286437(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20080812347 |
申请日期 |
2008.01.10 |
申请人 |
ZHANG FULI;HU MENG;XIE MEIHUA;LAI ANPING;SUN RENTONG;CHEN DAOXIN;BAO RUSHENG;BAI HUA |
发明人 |
ZHANG FULI;HU MENG;XIE MEIHUA;LAI ANPING;SUN RENTONG;CHEN DAOXIN;BAO RUSHENG;BAI HUA |
分类号 |
C07C271/44;C07C215/50;C07C269/04 |
主分类号 |
C07C271/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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