发明名称 |
SINGLE EXPRESSION VECTOR FOR GENERATION OF A VIRUS WITH A SEGMENTED GENOME |
摘要 |
The present invention encompasses an expression vector that is capable of generating a virus from a segmented genome. In particular, a single expression vector may be utilized to produce influenza virus in cultured cells. The expression vector can be delivered in a purified DNA form or by a suitably designed bacterial carrier to cells in culture or to animals. This invention increases the virus generation efficiency, which benefits vaccine development. The bacterial carrier harboring such a plasmid encoding an attenuated virus may be used as a vaccine against corresponding viral disease.
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申请公布号 |
US2010285592(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20100759842 |
申请日期 |
2010.04.14 |
申请人 |
THE ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OFARIZONA STATE UNIVERSITY |
发明人 |
CURTISS, III ROY;ZHANG XIANGMIN |
分类号 |
C12N15/64;C12N15/63 |
主分类号 |
C12N15/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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