发明名称 |
Erythrocyte-encapsulated L-asparaginase for enhanced acute lymphoblastic leukemia therapy |
摘要 |
Compositions for transporting L-asparaginase across the cellular membrane of erythrocytes, comprising a low molecular weight protamine peptide. Process of preparation of compositions comprising conjugates of L-asparaginase and a low molecular weight protamine peptide. Method of treatment comprising administration of adapted L-asparaginase is also described.
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申请公布号 |
US2010284982(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20080318112 |
申请日期 |
2008.12.22 |
申请人 |
YANG VICTOR C;KWON YOUNG M;CHUNG HEE S;YANG ARTHUR J |
发明人 |
YANG VICTOR C.;KWON YOUNG M.;CHUNG HEE S.;YANG ARTHUR J. |
分类号 |
A61K35/18;A61P35/00;A61P35/02;C12N9/82;C12N9/96 |
主分类号 |
A61K35/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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