| 发明名称 |
HYDRAZIDE COMPOUNDS AS THYROID HORMONE RECEPTOR MODULATORS AND USES THEREOF |
| 摘要 |
A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant thyroid hormone activity, such as hyperthyroidism and thyrotoxicosis.
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| 申请公布号 |
US2010286182(A1) |
申请公布日期 |
2010.11.11 |
| 申请号 |
US20080450922 |
申请日期 |
2008.04.18 |
| 申请人 |
SAMUELS HERBERT H;ABAGYAN RUBEN;SCHAPIRA MATTHIEU;TOTROV MAXIM;RAAKA BRUCE M;WILSON STEPHEN R;FAN LI;ZHOU ZHIGUO |
发明人 |
SAMUELS HERBERT H.;ABAGYAN RUBEN;SCHAPIRA MATTHIEU;TOTROV MAXIM;RAAKA BRUCE M.;WILSON STEPHEN R.;FAN LI;ZHOU ZHIGUO |
| 分类号 |
A61K31/438;A61K31/4418;A61P5/16;C07D211/70;C07D471/10 |
主分类号 |
A61K31/438 |
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