发明名称 |
PREDICTION OF SCHIZOPHRENIA RISK USING HOMOZYGOUS GENETIC MARKERS |
摘要 |
Provided are methods of identifying a genetic profile influencing the relative probability of a subject manifesting a phenotype that is at least partially heritable. Also provided are methods of determining the relative likelihood that a subject will manifest a phenotype that is at least partially heritable. Additionally, methods of determining the relative risk of a human subject for manifesting schizophrenia are provided. Further provided are methods of screening a human embryo in vitro for the risk of becoming a human manifesting schizophrenia. Also, methods of identifying a single nucleotide polymorphism (SNP) variant affecting the risk of a human subject for manifesting schizophrenia are provided. Methods of screening for a compound that may affect schizophrenia are additionally provided.
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申请公布号 |
US2010285455(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20080452097 |
申请日期 |
2008.06.10 |
申请人 |
THE FEINSTEIN INSTITUTE MEDICAL RESEARCH |
发明人 |
LENCZ TODD;MALHOTRA ANIL K.;KANE JOHN M. |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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地址 |
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