发明名称 |
NOVEL COMPOUNDS OF REVERSE TURN MIMETICS AND THE USE THEREOF |
摘要 |
Conformationally constrained compounds that are novel and mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins and having bicyclic framework are disclosed, as well as their prodrugs. Such reverse-turn mimetic structures and pro-drugs have utility over a wide range of fields, including use as diagnostic and therapeutic agents. The invention also relates to a use of such compounds for the preparation of a medicament for treating or preventing cancer including an acute myeloid leukemia.
|
申请公布号 |
US2010286094(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20080738066 |
申请日期 |
2008.10.15 |
申请人 |
CHOONGWAE PHARMA CORPORATION |
发明人 |
CHUNG JAE UK;JUNG KYUNG-YUN;JEONG MIN-WOOK;JUNG HEE-KYUNG;LA HYUN-JU |
分类号 |
A61K31/53;A61K31/5377;A61K31/675;A61P35/02;C07D487/04 |
主分类号 |
A61K31/53 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|